Journal: PLoS ONE

Article Title: Differential Requirement for c-Jun N-terminal Kinase 1 in Lung Inflammation and Host Defense

doi: 10.1371/journal.pone.0034638

Figure Lengend Snippet: WT and JNK1 −/− mice were challenged with 10 7 cfu of E. coli for 24 hours (N = 8, 10). A – bacterial colony counts in lung homogenate. B – inflammatory cells in BAL fluid. C, D – inflammatory cytokines in lung homogenate. E – antimicrobial peptide expression in lung tissue. F – inflammatory cells in BAL fluid from mice challenged with PBS for 24 hours (N = 6, 6). * p<0.05, # p<0.10.

Article Snippet: JNK1 −/− and WT mice were inoculated with Escherichia coli (DH5α, 10 7 cfu) or Staphylococcus aureus (ATCC 49775, 10 8 cfu) by oropharyngeal aspiration in 50 μl of sterile PBS.

Techniques: Expressing

Journal: PLoS ONE

Article Title: Differential Requirement for c-Jun N-terminal Kinase 1 in Lung Inflammation and Host Defense

doi: 10.1371/journal.pone.0034638

Figure Lengend Snippet: WT and JNK1 −/− mice were challenged with 10 7 cfu of E. coli for 24 hours (N = 8, 10). A – lung histology 100× (top panels), 200× (lower panels). B – lung histology scoring. * p<0.05.

Article Snippet: JNK1 −/− and WT mice were inoculated with Escherichia coli (DH5α, 10 7 cfu) or Staphylococcus aureus (ATCC 49775, 10 8 cfu) by oropharyngeal aspiration in 50 μl of sterile PBS.

Techniques: